Description
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Abstract:
Methylene Blue is believed to be the oldest synthesized medication. Its history in the treatment of methemoglobinemia is well known but its activity as a potential mitochondrial rescue agent is only emerging. In this CME Dr. Anderson will discuss the chemistry and pharmacology of this unique molecule. Additionally, he will relate modern uses of methylene blue in various disease states. The presentation will focus on safety, proper prescribing (oral and parenteral), and safe versus contraindicated co-therapies.
Objectives:
- Define the structure of methylene blue
- Describe standard therapeutic uses
- Describe its effect on the mitochondria
- Define new uses for it
- Describe dosing and safety parameters
CME Outline:
- Methylene Blue chemistry and pharmacology
- Methylene Blue standard of care
- Methylene Blue mitochondrial pharmacology
- Pharmacological parameters:
- Dosing PO
- Dosing IV
- Toxicity
- Clinical pharmacology
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