QUESTION: I have an inquiry about a patient with a past history of Ca Oxalate stones who is recently dx’d with Prostate Cancer. The diagnosis is one where the cancer is inoperable and there are mets to the bone, however the patient is asymptomatic. Bloodwork prior to starting IV therapy came back with all lab results WNL, including kd function. I slowly have been titrating him up to 50g Vitamin C. He has noticed now that we are at 50g that he has increased urgency to urinate. He has no pain or burning sensation, just urgency. He was only getting IV’s once a week. He has only had 2 bags with 50g, the others were 6g (vitamin mineral bag), 15g (vitamin mineral IV), 25, 35 and 50g. Am I doing the wrong thing by incorporating IVC with a patient with a history of calcium stones? His kidney function tests show that his kidneys are clearing fine with no lag to increase stone formation. But maybe something has changed in the last month? I would suspect some imaging of the kidneys would be warranted. Should I just discontinue the IVC on this patient?
ANSWER: The increased urination urgency is common in prostate disease with HDIVC. It is a reason we have had to stop, but we leave it up to the patient – and they may choose to not continue. The osmolarity is a reason for the increased prostate reactivity. As for the IVC and Kidney Stones: Need to monitor Ki FCT as often as needed (I’d do q-4 weeks then q-8 weeks etc. Also I’d do the more “pure” IVC formulas I have shared with just C, K-Mg-Ca. In folks who form stones I also recommend 100 mg B-6 as oxalates are shown to be reduced via Magnesium and B-6. Just watch the patient, kidneys and labs. With an inoperable late stage you pretty much can do whatever the patient is up for.
