QUESTION: I’m wondering what your favorite IV formulas for Parkinson’s disease are? I’ve been working with glutathione 10ml of 200mg/ml and sometimes add B-complex in. I’ll bet some of you….especially the ever-resourceful Paul Anderson have some tips on other things I might add to achieve better results. I finally have a patient who can afford regular IVs for Parkinson’s so I would be interested in the frequency of IVs that you’ve seen results with as well.
ANSWER: In my experience, the augmentation of the GSH is more important in neurological disease than the GSH. I usually do the GSH augment IV + GSH 2x a week for 4-8 weeks then weekly for another 8-12 then reassess. In some the addition of a PTC bag is a good synergist, and in some PolyMVA as an added bag is better.
This is a slightly more generalized version of the glutathione augmentation formula “basis”.
The bottom line is that most people (and especially with neurodegeneration) have deficits in two areas that make simply administering GSH (although an “OK” idea) less efficient. The first area is the actual co-factor matrix for GSH to work more than one time through the ReDox cycle. Those co-factors and their basis in the data are listed in this document, and in clinical practice (first on radiation injury and then neurodegeneration) this approach really did work much better than GSH alone.
The second area is the overall ReDox triplet stability (which basically continues the cycling of GSH in the larger context. There you have the stabilization of GSH activity across compartments. That is largely taken care of by the co-factors in the IV, but also involves membrane stability factors such as Oral Tocopherols, Omegas and IV and Oral Phospholipids like Phosphatidylcholine (“PTC”). The general point being that if you support the entire system you get better results (sounds terribly naturopathic, I know…)